Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4687592

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against ZIKV infected in human neural progenitor cells incubated with cells for 24 hrs prior to viral infection followed by replacement of fresh medium containing compound and measured at 48 hrs post infection by RT-PCR method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Zika virus
Cell Type Neural Progenitor Cell
Confidence 1 — Organism
Curated By Autocuration

Target

Zika virus (CHEMBL4296612)
Type ORGANISM
Organism Zika virus

Publication

Modulating microRNA Processing: Enoxacin, the Progenitor of a New Class of Drugs.
Felicetti T,Cecchetti V,Manfroni G
J Med Chem (2020) 63 : 12275 -12289
PubMed 32672457 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.28 4.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL826 ENOXACIN 4.0 1 4.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL826 ENOXACIN IC50 = 51990.0 nM 4.28