Assay Detail
Binding
CHEMBL4687634
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat NTPDase2 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Ectonucleoside triphosphate diphosphohydrolase 2 (CHEMBL3300) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Targeting Metabolism of Extracellular Nucleotides via Inhibition of Ectonucleotidases CD73 and CD39.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.70 | 4.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL271673 | — | — | 1 | 4.75 |
| CHEMBL597197 | — | — | 1 | 4.72 |
| CHEMBL4744335 | — | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL271673 | — | Ki | = | 18000.0 | nM | 4.75 |
| CHEMBL597197 | — | Ki | = | 19100.0 | nM | 4.72 |
| CHEMBL4744335 | — | Ki | = | 24200.0 | nM | 4.62 |