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Assay Detail

CHEMBL4687639

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Activation of recombinant human GPR55 expressed in HEK293 cells assessed as increase in [35S]-GTPgammaS stimulation incubated for 60 min by scintillation counting method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HEK293
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

G-protein coupled receptor 55 (CHEMBL1075322)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The Essential Medicinal Chemistry of Cannabidiol (CBD).
Nelson KM,Bisson J,Singh G,Graham JG,Chen SN,Friesen JB,Dahlin JL,Niemitz M,Walters MA,Pauli GF
J Med Chem (2020) 63 : 12137 -12155
PubMed 32804502 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 8.70 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL499876 1 8.70
CHEMBL3402654 1 8.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL499876 EC50 = 2.0 nM 8.70
CHEMBL3402654 EC50 = 2.0 nM 8.70