Assay Detail
Binding
CHEMBL4687793
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-MK801 from NMDA receptor in rat brain membranes
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Glutamate NMDA receptor (CHEMBL1907608) ↗| Type | PROTEIN COMPLEX GROUP |
| Organism | Rattus norvegicus |
Publication
Repurposing of Drugs-The Ketamine Story.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.80 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL395091 | ESKETAMINE | 4.0 | 1 | 6.16 |
| CHEMBL467126 | — | — | 1 | 5.65 |
| CHEMBL467505 | — | — | 1 | 5.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL395091 | ESKETAMINE | Ki | = | 690.0 | nM | 6.16 |
| CHEMBL467126 | — | Ki | = | 2250.0 | nM | 5.65 |
| CHEMBL467505 | — | Ki | = | 2570.0 | nM | 5.59 |