Assay Detail
Functional
CHEMBL4688084
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Anticancer activity against human T84 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T84 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.27 | 8.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92 | DOCETAXEL ANHYDROUS | 4.0 | 1 | 8.57 |
| CHEMBL481 | IRINOTECAN | 4.0 | 1 | 8.16 |
| CHEMBL4789041 | — | — | 1 | 8.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92 | DOCETAXEL ANHYDROUS | IC50 | = | 2.7 | nM | 8.57 |
| CHEMBL481 | IRINOTECAN | IC50 | = | 6.9 | nM | 8.16 |
| CHEMBL4789041 | — | IC50 | = | 8.2 | nM | 8.09 |