Assay Detail
Binding
CHEMBL4689446
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Staphylococcus aureus 70S ribosome assessed as dissociation constant by measuring reduction in BODIPY-Erythromycin A binding incubated for 1.5 hr by fluorescence polarization assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Staphylococcus aureus |
| Subcellular | Ribosome |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 8.62 | 8.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4128170 | — | — | 1 | 8.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4128170 | — | Kd | = | 2.4 | nM | 8.62 |