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Assay Detail

CHEMBL4689579

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]R-PIA from recombinant human A1AR measured after 60 mins by liquid scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Adenosine receptor A1 (CHEMBL226)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Biological Evaluation of 5'-(N-Ethylcarboxamido)adenosine Analogues as Grp94-Selective Inhibitors.
Tosh DK,Brackett CM,Jung YH,Gao ZG,Banerjee M,Blagg BSJ,Jacobson KA
ACS Med Chem Lett (2021) 12 : 373 -379
PubMed 33738064 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.30 7.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL193692 1 7.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL193692 Ki = 49.9 nM 7.30