Assay Detail
Functional
CHEMBL4700296
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Cowpox virus Grishak infected in African green monkey Vero cells assessed as reduction in cell survival incubated for 4 days by neutral red dye based colorimetric analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cowpox virus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New chemical agents based on adamantane-monoterpene conjugates against orthopoxvirus infections
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.12 | 5.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4759505 | — | — | 1 | 5.39 |
| CHEMBL4789170 | — | — | 1 | 5.33 |
| CHEMBL4777797 | — | — | 1 | 5.14 |
| CHEMBL4758977 | — | — | 1 | 4.90 |
| CHEMBL4748821 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4759505 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL4789170 | — | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL4777797 | — | IC50 | = | 7200.0 | nM | 5.14 |
| CHEMBL4758977 | — | IC50 | = | 12500.0 | nM | 4.90 |
| CHEMBL4748821 | — | IC50 | = | 15000.0 | nM | 4.82 |