Assay Detail
ADMET
CHEMBL4700779
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of OATP1B1 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Solute carrier organic anion transporter family member 1B1 (CHEMBL1697668) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification and Preclinical Evaluation of the Bicyclic Pyrimidine γ-Secretase Modulator BMS-932481.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.67 | 7.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4209316 | — | — | 1 | 7.18 |
| CHEMBL4794465 | — | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4209316 | — | IC50 | = | 66.0 | nM | 7.18 |
| CHEMBL4794465 | — | IC50 | = | 690.0 | nM | 6.16 |