Assay Detail
Binding
CHEMBL4701568
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of BRD4 BD2 (unknown origin) by ALPHAScreen assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.73 | 4.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3814752 | — | — | 1 | 4.73 |
| CHEMBL4795699 | — | — | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3814752 | — | IC50 | = | 18800.0 | nM | 4.73 |
| CHEMBL4795699 | — | IC50 | = | 19000.0 | nM | 4.72 |