Assay Detail
Functional
CHEMBL4703341
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Cytotoxicity against human MOLM-13 cells assessed as reduction in cell viability after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MOLM-13 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Biological Evaluation of Selected Flavonoids as Inhibitors of MNKs Targeting Acute Myeloid Leukemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.27 | 5.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL151 | LUTEOLIN | 2.0 | 1 | 5.35 |
| CHEMBL293776 | HISPIDULIN | — | 1 | 5.19 |
| CHEMBL210635 | GENKWANIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL151 | LUTEOLIN | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL293776 | HISPIDULIN | IC50 | = | 6400.0 | nM | 5.19 |
| CHEMBL210635 | GENKWANIN | IC50 | > | 10000.0 | nM | - |