Assay Detail
Binding
CHEMBL4705960
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MALT1 in human OCILY3 cells by NF-kappaB reporter gene assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | OCILY3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (CHEMBL3632452) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.40 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4748253 | — | — | 1 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4748253 | — | IC50 | = | 40.0 | nM | 7.40 |