Assay Detail
Binding
CHEMBL4707350
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PI3K2beta (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (CHEMBL5554) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Design, Synthesis, and Preclinical Evaluation of Fused Pyrimidine-Based Hydroxamates for the Treatment of Hepatocellular Carcinoma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.45 | 8.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4749655 | — | — | 1 | 8.31 |
| CHEMBL4744689 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4749655 | — | Kd | = | 4.9 | nM | 8.31 |
| CHEMBL4744689 | — | Kd | = | 260.0 | nM | 6.58 |