Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt O00750. Use UniProt O00750 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O00750 as the stable identity anchor, then attach disease evidence before program review.
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
Review this target as Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, mapped to UniProt O00750. Sequence length is 1634 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta as ChEMBL target CHEMBL5554, mapped to UniProt O00750. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O00750 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta |
| UniProt Accession | O00750 |
| Component Type | Protein |
| Sequence Length | 1634 aa |
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
Review this target as Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, mapped to UniProt O00750. Sequence length is 1634 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5803247 | 10.0 | Kd | 0.1 | Preclinical |
| CHEMBL5894050 | 9.7 | Kd | 0.2 | Preclinical |
| CHEMBL5878424 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL5877033 | 9.6 | IC50 | 0.251 | Preclinical |
| CHEMBL5831673 | 9.52 | Kd | 0.3 | Preclinical |
| CHEMBL3956037 | 9.4 | Kd | 0.4 | Preclinical |
| CHEMBL592445 | 9.34 | Kd | 0.46 | Clinical |
| CHEMBL5757074 | 9.3 | IC50 | 0.501 | Preclinical |
| CHEMBL5888478 | 9.3 | Kd | 0.5 | Preclinical |
| CHEMBL5268567 | 9.3 | Kd | 0.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 149 | 172 | 7.8 |
| assay format | 37 | 36 | 6.3 |
| cell-based format | 18 | 27 | 5.6 |
| subcellular format | 6 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |