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Assay Detail

CHEMBL4712170

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Functional
Agonist activity at human Gialpha-coupled GPR84 expressed in baculovirus infected sf9 insect cells assessed as induction of [35S]GTPgammaS incubated for 1 hr by liquid scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Sf9
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

G-protein coupled receptor 84 (CHEMBL3714079)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists.
Chen LH,Zhang Q,Xie X,Nan FJ
J Med Chem (2020) 63 : 15399 -15409
PubMed 33267584 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 4.89 4.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4288936 1 4.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4288936 EC50 = 13000.0 nM 4.89