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Assay Detail

CHEMBL4712355

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human RKO cells incubated for 72 hrs by Cell Titer-Glo luminescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type RKO
Confidence 1 — Organism
Curated By Autocuration

Target

RKO (CHEMBL614879)
Type CELL-LINE
Organism Homo sapiens

Publication

Development of Potential Antitumor Agents from the Scaffolds of Plant-Derived Terpenoid Lactones.
Ren Y,Kinghorn AD
J Med Chem (2020) 63 : 15410 -15448
PubMed 33289552 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.82 7.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL205190 TRIPTONIDE 1 7.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL205190 TRIPTONIDE IC50 = 15.0 nM 7.82