RKO · CELL-LINE · Homo sapiens
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RKO
Review this target as RKO.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats RKO as ChEMBL target CHEMBL614879. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | RKO |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as RKO.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL888 | 10.56 | IC50 | 0.02785 | Approved |
| CHEMBL94657 | 10.19 | IC50 | 0.06474 | Clinical |
| CHEMBL1221966 | 9.42 | IC50 | 0.38 | Preclinical |
| CHEMBL395810 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL3545252 | 9.01 | IC50 | 0.9888 | Approved |
| CHEMBL325041 | 8.97 | IC50 | 1.061 | Clinical |
| CHEMBL3126408 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL553025 | 8.82 | IC50 | 1.52 | Approved |
| CHEMBL96926 | 8.79 | IC50 | 1.61 | Preclinical |
| CHEMBL3128043 | 8.74 | IC50 | 1.8 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 593 | 805 | 5.8 |
| organism-based format | 21 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 8 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 0 | — |