Assay Detail
Binding
CHEMBL4712504
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to STAT3 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Signal transducer and activator of transcription 3 (CHEMBL4026) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of Novel Azetidine Amides as Potent Small-Molecule STAT3 Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.04 | 6.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4777016 | — | — | 1 | 6.06 |
| CHEMBL4787896 | — | — | 1 | 6.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4777016 | — | Kd | = | 880.0 | nM | 6.06 |
| CHEMBL4787896 | — | Kd | = | 960.0 | nM | 6.02 |