Assay Detail
Binding
CHEMBL4713577
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human thrombin
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
How a Fragment Draws Attention to Selectivity Discriminating Features between the Related Proteases Trypsin and Thrombin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.75 | 9.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL312145 | — | — | 1 | 9.26 |
| CHEMBL321130 | — | — | 1 | 6.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL312145 | — | Kd | = | 0.55 | nM | 9.26 |
| CHEMBL321130 | — | Kd | = | 590.0 | nM | 6.23 |