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Assay Detail

CHEMBL4714150

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Binding
Inhibition of DPP9 (unknown origin) using AMC substrate by fluorometric assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Dipeptidyl peptidase 9 (CHEMBL4793)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Identification of BR102910 as a selective fibroblast activation protein (FAP) inhibitor.
Jung HJ,Nam EH,Park JY,Ghosh P,Kim IS
Bioorg Med Chem Lett (2021) 37 : 127846 -127846
PubMed 33571650 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.90 4.90

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3233842 1 4.90
CHEMBL4747683 1 -
CHEMBL2333026 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3233842 IC50 = 12500.0 nM 4.90
CHEMBL4747683 IC50 > 100000.0 nM -
CHEMBL2333026 IC50 > 100000.0 nM -