Assay Detail
Functional
CHEMBL4714522
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human HT-1080 cells assessed as reduction in cell proliferation measured after 48 hrs by CCK8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-1080 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Withanolides from dietary tomatillo suppress HT1080 cancer cell growth by targeting mutant IDH1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.62 | 5.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL504910 | — | — | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL504910 | — | IC50 | = | 2410.0 | nM | 5.62 |