Assay Detail
Functional
CHEMBL4715459
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human SU-DHL-1 cells assessed as cell growth inhibition incubated for 4 days by CellTiter-Glo asssay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SU-DHL-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.53 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4776801 | — | — | 1 | 5.58 |
| CHEMBL4452527 | — | — | 1 | 5.47 |
| CHEMBL4575382 | — | — | 1 | - |
| CHEMBL4796524 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4776801 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL4452527 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL4575382 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4796524 | — | IC50 | > | 10000.0 | nM | - |