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Assay Detail

CHEMBL4715937

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of F-neo from premature miRNA21 (unknown origin) by fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Not specified
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Target

microRNA 21 (CHEMBL1615322)
Type NUCLEIC-ACID
Organism Homo sapiens

Publication

Targeting miRNA by tunable small molecule binders: peptidic aminosugar mediated interference in miR-21 biogenesis reverts epithelial to mesenchymal transition
Ghosh, Arpita, Degyatoreva, Natalya, Kukielski, Casey, Story, Sandra, Bhaduri, Sayantan, Maiti, Krishnagopal, Nahar, Smita, Ray, Arjun, Arya, Dev P., Maiti, Souvik
Medchemcomm (2018) 9 : 1147 -1154
PubMed 30109002 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.96 5.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1384 KANAMYCIN 4.0 1 5.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1384 KANAMYCIN IC50 = 1102.0 nM 5.96