Assay Detail
Binding
CHEMBL4719519
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CLK4 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Dual specificity protein kinase CLK4 (CHEMBL4203) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
An Unusual Binding Model of the Methyl 9-Anilinothiazolo[5,4-f] quinazoline-2-carbimidates (EHT 1610 and EHT 5372) Confers High Selectivity for Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.37 | 7.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3894571 | — | — | 1 | 7.50 |
| CHEMBL2386747 | — | — | 1 | 7.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3894571 | — | IC50 | = | 32.0 | nM | 7.50 |
| CHEMBL2386747 | — | IC50 | = | 59.0 | nM | 7.23 |