Assay Detail
Binding
CHEMBL4723102
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Inhibition of mushroom tyrosinase using L-tyrosine as substrate by spectrophotometric method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Advances in the Design of Genuine Human Tyrosinase Inhibitors for Targeting Melanogenesis and Related Pigmentations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.22 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3961037 | — | — | 1 | 6.52 |
| CHEMBL443605 | HEXYLRESORCINOL | -1.0 | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3961037 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL443605 | HEXYLRESORCINOL | IC50 | = | 1200.0 | nM | 5.92 |