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Assay Detail

CHEMBL4725019

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human factor Xa using S-2238 as substrate by chromogenic assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Coagulation factor X (CHEMBL244)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Investigation on the Anticancer Activity of Symmetric and Unsymmetric Cyclic Sulfamides.
Jun JJ,Duscharla D,Ummanni R,Hanson PR,Malhotra SV
ACS Med Chem Lett (2021) 12 : 202 -210
PubMed 33603966 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.40 9.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4746164 1 9.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4746164 IC50 = 0.4 nM 9.40