Assay Detail
Functional
CHEMBL4726183
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse anti-human anti-IgD-stimulated CD86 cell surface expression in human whole blood preincubated for 2 hrs followed by anti-human anti-IgD stimulation for 18 hrs by flow cytometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Blood |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of quinoline-based irreversible BTK inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.57 | 6.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4752700 | — | — | 1 | 6.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4752700 | — | EC50 | = | 267.0 | nM | 6.57 |