Assay Detail
Binding
CHEMBL4731083
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Displacement of [3H]-SCH23390 from human D1 receptor expressed in HEK293 cells after 60 mins by microbeta counting based assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Exception That Proves the Rule: Investigation of Privileged Stereochemistry in Designing Dopamine DR Bitopic Agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 12 | 5.25 | 5.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4551160 | — | — | 1 | 5.25 |
| CHEMBL4464060 | — | — | 1 | - |
| CHEMBL4764883 | — | — | 1 | - |
| CHEMBL4744811 | — | — | 1 | - |
| CHEMBL4791884 | — | — | 1 | - |
| CHEMBL4778398 | — | — | 1 | - |
| CHEMBL97424 | — | — | 1 | - |
| CHEMBL70565 | — | — | 1 | - |
| CHEMBL317493 | — | — | 1 | - |
| CHEMBL4458742 | — | — | 1 | - |
| CHEMBL4452064 | — | — | 1 | - |
| CHEMBL4437740 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4551160 | — | Ki | = | 5630.0 | nM | 5.25 |
| CHEMBL4464060 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL4764883 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL4744811 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL4791884 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL4778398 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL97424 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL70565 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL317493 | — | Ki | - | — | - | |
| CHEMBL4458742 | — | Ki | - | — | - | |
| CHEMBL4452064 | — | Ki | - | — | - | |
| CHEMBL4437740 | — | Ki | - | — | - |