Assay Detail
ADMET
CHEMBL4732773
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Cytotoxicity against human HaCaT cells after 24 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HaCaT |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Sulfonium-based liposome-encapsulated antibiotics deliver a synergistic antibacterial activity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.73 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1440 | TETRACYCLINE | 4.0 | 1 | 5.10 |
| CHEMBL4751685 | — | — | 1 | 4.57 |
| CHEMBL1082 | AMOXICILLIN | 4.0 | 1 | 4.53 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1440 | TETRACYCLINE | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL4751685 | — | IC50 | = | 27000.0 | nM | 4.57 |
| CHEMBL1082 | AMOXICILLIN | IC50 | = | 29410.0 | nM | 4.53 |