Assay Detail
Binding
CHEMBL4732780
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Inhibition of human AChE
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Studies on the affinity of 6-[(n-(cyclo)aminoalkyl)oxy]-4H-chromen-4-ones for sigma 1/2 receptors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.94 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4780719 | — | — | 1 | 5.43 |
| CHEMBL4776765 | — | — | 1 | 5.25 |
| CHEMBL4778990 | — | — | 1 | 5.14 |
| CHEMBL4754186 | — | — | 1 | 4.97 |
| CHEMBL4778747 | — | — | 1 | 4.80 |
| CHEMBL4781384 | — | — | 1 | 4.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4780719 | — | IC50 | = | 3740.0 | nM | 5.43 |
| CHEMBL4776765 | — | IC50 | = | 5580.0 | nM | 5.25 |
| CHEMBL4778990 | — | IC50 | = | 7200.0 | nM | 5.14 |
| CHEMBL4754186 | — | IC50 | = | 10600.0 | nM | 4.97 |
| CHEMBL4778747 | — | IC50 | = | 15900.0 | nM | 4.80 |
| CHEMBL4781384 | — | IC50 | = | 96200.0 | nM | 4.02 |