Assay Detail
Binding
CHEMBL4732948
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PMA-induced human skin fibroblast derived MMP1 by fluorometric assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Fibroblast |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Amide Bond Bioisosteres: Strategies, Synthesis, and Successes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.86 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL432991 | — | — | 1 | 8.96 |
| CHEMBL4785595 | — | — | 1 | 8.96 |
| CHEMBL4791227 | — | — | 1 | 8.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL432991 | — | IC50 | = | 1.1 | nM | 8.96 |
| CHEMBL4785595 | — | IC50 | = | 1.1 | nM | 8.96 |
| CHEMBL4791227 | — | IC50 | = | 2.2 | nM | 8.66 |