Assay Detail
Functional
CHEMBL4736092
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Cytotoxicity in human BT-549 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | BT-549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel N-Methylated Cyclodepsipeptide Prodrugs for Targeted Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.67 | 7.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4210516 | — | — | 1 | 7.75 |
| CHEMBL4785660 | — | — | 1 | 5.58 |
| CHEMBL4786013 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4210516 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL4785660 | — | IC50 | = | 2650.0 | nM | 5.58 |
| CHEMBL4786013 | — | IC50 | - | — | - |