Assay Detail
Binding
CHEMBL4738569
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CYP4Z1 overexpressed in human MCF7 cells using luciferin-BE as substrate incubated for 24 hrs followed by substrate addition by luminescence based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a novel potent cytochrome P450 CYP4Z1 inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.23 | 5.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL14192 | BENZYLIMIDAZOLE | — | 1 | 5.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL14192 | BENZYLIMIDAZOLE | IC50 | = | 5900.0 | nM | 5.23 |