Assay Detail
Functional
CHEMBL4739244
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Antiproliferative activity against human U-87MG cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-87MG ATCC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Evaluation of the antiproliferative activity of 106 marine microbial metabolites against human lung cancer cells and potential antiproliferative mechanism of purpuride G.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.29 | 5.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4743394 | — | — | 1 | 5.97 |
| CHEMBL4789700 | — | — | 1 | 4.98 |
| CHEMBL4790096 | — | — | 1 | 4.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4743394 | — | IC50 | = | 1060.0 | nM | 5.97 |
| CHEMBL4789700 | — | IC50 | = | 10400.0 | nM | 4.98 |
| CHEMBL4790096 | — | IC50 | = | 12400.0 | nM | 4.91 |