Assay Detail
ADMET
CHEMBL4771733
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Cytotoxicity against rat L6 cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Cell Type | L6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis and antimicrobial evaluation of novel glycosylated-fluoroquinolones derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.36 | 5.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1202 | CIPROFLOXACIN HYDROCHLORIDE | 4.0 | 1 | 5.47 |
| CHEMBL9 | NORFLOXACIN | 4.0 | 1 | 5.46 |
| CHEMBL4780174 | — | — | 1 | 5.44 |
| CHEMBL4793108 | — | — | 1 | 5.43 |
| CHEMBL4798472 | — | — | 1 | 5.39 |
| CHEMBL4791119 | — | — | 1 | 5.29 |
| CHEMBL4776749 | — | — | 1 | 5.27 |
| CHEMBL4777869 | — | — | 1 | 5.26 |
| CHEMBL32 | MOXIFLOXACIN | 4.0 | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1202 | CIPROFLOXACIN HYDROCHLORIDE | IC50 | = | 3399.8 | nM | 5.47 |
| CHEMBL9 | NORFLOXACIN | IC50 | = | 3431.1 | nM | 5.46 |
| CHEMBL4780174 | — | IC50 | = | 3616.4 | nM | 5.44 |
| CHEMBL4793108 | — | IC50 | = | 3724.9 | nM | 5.43 |
| CHEMBL4798472 | — | IC50 | = | 4027.0 | nM | 5.39 |
| CHEMBL4791119 | — | IC50 | = | 5076.5 | nM | 5.29 |
| CHEMBL4776749 | — | IC50 | = | 5316.7 | nM | 5.27 |
| CHEMBL4777869 | — | IC50 | = | 5525.7 | nM | 5.26 |
| CHEMBL32 | MOXIFLOXACIN | IC50 | = | 5778.3 | nM | 5.24 |