Assay Detail
Binding
CHEMBL4772311
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]8-OH-DPAT from 5HT-1A receptor in rat hippocampal membrane incubated for 20 mins by competitive binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Hippocampus |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel anilide and benzylamide derivatives of arylpiperazinylalkanoic acids as 5-HT/5-HT receptor antagonists and phosphodiesterase 4/7 inhibitors with procognitive and antidepressant activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.59 | 6.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL376662 | — | — | 1 | 6.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL376662 | — | Ki | = | 254.0 | nM | 6.59 |