Assay Detail
ADMET
CHEMBL4773304
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Cytotoxicity against CHO cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Cricetulus griseus |
| Cell Type | CHO |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of geniposide derivatives as potent and selective PTPlB inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.30 | 4.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4785543 | — | — | 1 | 4.38 |
| CHEMBL4787688 | — | — | 1 | 4.21 |
| CHEMBL4786441 | — | — | 1 | - |
| CHEMBL4788887 | — | — | 1 | - |
| CHEMBL4798517 | — | — | 1 | - |
| CHEMBL4782460 | — | — | 1 | - |
| CHEMBL4788294 | — | — | 1 | - |
| CHEMBL4782087 | — | — | 1 | - |
| CHEMBL4793462 | — | — | 1 | - |
| CHEMBL4800140 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4785543 | — | IC50 | = | 42000.0 | nM | 4.38 |
| CHEMBL4787688 | — | IC50 | = | 62000.0 | nM | 4.21 |
| CHEMBL4786441 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL4788887 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL4798517 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL4782460 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL4788294 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL4782087 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL4793462 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL4800140 | — | IC50 | > | 200000.0 | nM | - |