Assay Detail
Functional
CHEMBL4774446
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antigiardial activity against Giardia duodenalis Ec1 incubated for 3 days by fluorescence method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Giardia intestinalis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anti-Giardia Drug Discovery: Current Status and Gut Feelings.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.69 | 7.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1483 | ALBENDAZOLE | 4.0 | 1 | 7.26 |
| CHEMBL1220 | TINIDAZOLE | 4.0 | 1 | 6.52 |
| CHEMBL137 | METRONIDAZOLE | 4.0 | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1483 | ALBENDAZOLE | IC50 | = | 55.0 | nM | 7.26 |
| CHEMBL1220 | TINIDAZOLE | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL137 | METRONIDAZOLE | IC50 | = | 500.0 | nM | 6.30 |