Assay Detail
Functional
CHEMBL4774483
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Antigiardial activity against Giardia intestinalis IMSS:0696:1 incubated for 48 hrs followed by wash out by hemocytometric counting method
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Giardia intestinalis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anti-Giardia Drug Discovery: Current Status and Gut Feelings.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 6.15 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4797147 | — | — | 1 | 6.30 |
| CHEMBL4789562 | — | — | 1 | 6.30 |
| CHEMBL4785337 | — | — | 1 | 6.30 |
| CHEMBL4795256 | — | — | 1 | 6.30 |
| CHEMBL1589212 | — | — | 1 | 6.30 |
| CHEMBL4800345 | — | — | 1 | 6.30 |
| CHEMBL4794900 | — | — | 1 | 6.30 |
| CHEMBL4790450 | — | — | 1 | 6.30 |
| CHEMBL4780569 | — | — | 1 | 6.30 |
| CHEMBL4793379 | — | — | 1 | 6.30 |
| CHEMBL498847 | SECNIDAZOLE | 4.0 | 1 | 5.39 |
| CHEMBL137 | METRONIDAZOLE | 4.0 | 1 | 5.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4797147 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4789562 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4785337 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4795256 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL1589212 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4800345 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4794900 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4790450 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4780569 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4793379 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL498847 | SECNIDAZOLE | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL137 | METRONIDAZOLE | IC50 | = | 4400.0 | nM | 5.36 |