Assay Detail
Binding
CHEMBL4775268
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Binding affinity to human PDL1 assessed as reduction in PDL1/human PD1protein-protein interaction by HTRF binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent Advances in the Development of PD-L1 Modulators: Degraders, Downregulators, and Covalent Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4776444 | — | — | 1 | 9.00 |
| CHEMBL4785255 | — | — | 1 | 9.00 |
| CHEMBL4776700 | — | — | 1 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4776444 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL4785255 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL4776700 | — | IC50 | = | 1.0 | nM | 9.00 |