Assay Detail
Binding
CHEMBL4806847
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human RIOK2 by DiscoverX assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase RIO2 (CHEMBL6000) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
3-amino-4-(4-(4 (dimethylcarbamoyl) phenyl)-1,4-diazepan-1-yl) thieno [2,3-b] pyridine-2-carboxamide for use in cancer therapy and formulations comprising the same
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.76 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2348353 | — | — | 1 | 6.89 |
| CHEMBL2348350 | — | — | 1 | 6.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2348353 | — | Kd | = | 130.0 | nM | 6.89 |
| CHEMBL2348350 | — | Kd | = | 240.0 | nM | 6.62 |