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Assay Detail

CHEMBL4808708

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to 5HT1D (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 1D (CHEMBL1983)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Structure-Activity Relationship of Heterocyclic P2Y<sub>14</sub> Receptor Antagonists: Removal of the Zwitterionic Character with Piperidine Bioisosteres.
Jung YH, Salmaso V, Wen Z, Bennett JM, Phung NB, Lieberman DI, Gopinatth V, Randle JCR, Chen Z, Salvemini D, Karcz TP, Cook DN, Jacobson KA.
J Med Chem (2021) 64 : 5099 -5122
PubMed 33787273 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.76 5.76

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4642592 1 5.76

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4642592 Ki = 1750.0 nM 5.76