Assay Detail
Functional
CHEMBL4808893
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at human GIPR expressed in HEK293 cells assessed as inhibition of GIP-induced cAMP production
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Gastric inhibitory polypeptide receptor (CHEMBL4383) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Optimization of Truncated Glucagon Peptides to Achieve Selective, High Potency, Full Antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.22 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4857523 | — | — | 1 | 7.22 |
| CHEMBL4876736 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4857523 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL4876736 | — | IC50 | > | 1000.0 | nM | - |