Assay Detail
ADMET
CHEMBL4809877
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Cytotoxicity against human RWPE-1 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | RWPE-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cyclopentenone-Containing Tetrahydroquinoline and Geldanamycin Alkaloids from <i>Streptomyces malaysiensis</i> as Potential Anti-Androgens against Prostate Cancer Cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.05 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4851816 | — | — | 1 | 6.68 |
| CHEMBL278315 | GELDANAMYCIN | 2.0 | 1 | 5.42 |
| CHEMBL1082407 | ENZALUTAMIDE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4851816 | — | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL278315 | GELDANAMYCIN | IC50 | = | 3800.0 | nM | 5.42 |
| CHEMBL1082407 | ENZALUTAMIDE | IC50 | > | 40000.0 | nM | - |