Assay Detail
Binding
CHEMBL4812890
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Inhibition of recombinant human liver CatK using Z-FR-AMC as substrate by fluorescence assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Nitrile-based peptoids as cysteine protease inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.08 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4846908 | — | — | 1 | 6.60 |
| CHEMBL4869291 | — | — | 1 | 6.50 |
| CHEMBL4852162 | — | — | 1 | 6.40 |
| CHEMBL4463665 | — | — | 1 | 6.40 |
| CHEMBL4875557 | — | — | 1 | 5.60 |
| CHEMBL4857068 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4846908 | — | Ki | = | 251.19 | nM | 6.60 |
| CHEMBL4869291 | — | Ki | = | 316.23 | nM | 6.50 |
| CHEMBL4852162 | — | Ki | = | 398.11 | nM | 6.40 |
| CHEMBL4463665 | — | Ki | = | 398.11 | nM | 6.40 |
| CHEMBL4875557 | — | Ki | = | 2511.89 | nM | 5.60 |
| CHEMBL4857068 | — | Ki | = | 10000.0 | nM | 5.00 |