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Assay Detail

CHEMBL4814684

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti-trichomonas activity against Trichomonas vaginalis JT incubated for 48 hrs by hemocytometer based eosin exclusion assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Trichomonas vaginalis
Confidence 1 — Organism
Curated By Autocuration

Target

Trichomonas vaginalis (CHEMBL612884)
Type ORGANISM
Organism Trichomonas vaginalis

Publication

Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective.
Patel OPS, Jesumoroti OJ, Legoabe LJ, Beteck RM.
Eur J Med Chem (2021) 210 : 112994 -112994
PubMed 33234343 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.70 8.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1080623 1 8.22
CHEMBL137 METRONIDAZOLE 4.0 1 7.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1080623 IC50 = 6.0 nM 8.22
CHEMBL137 METRONIDAZOLE IC50 = 68.0 nM 7.17