Assay Detail
Functional
CHEMBL4814686
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antigiardial activity against Giardia intestinalis MSS:0696:1 incubated for 48 hrs
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Giardia intestinalis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.83 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4797147 | — | — | 1 | 6.34 |
| CHEMBL1589212 | — | — | 1 | 6.07 |
| CHEMBL4789562 | — | — | 1 | 6.01 |
| CHEMBL137 | METRONIDAZOLE | 4.0 | 1 | 5.36 |
| CHEMBL498847 | SECNIDAZOLE | 4.0 | 1 | 5.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4797147 | — | IC50 | = | 460.0 | nM | 6.34 |
| CHEMBL1589212 | — | IC50 | = | 860.0 | nM | 6.07 |
| CHEMBL4789562 | — | IC50 | = | 980.0 | nM | 6.01 |
| CHEMBL137 | METRONIDAZOLE | IC50 | = | 4420.0 | nM | 5.36 |
| CHEMBL498847 | SECNIDAZOLE | IC50 | = | 4410.0 | nM | 5.36 |