Assay Detail
Binding
CHEMBL4814799
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-DPDPE from human delta opioid receptor expressed in CHO-K1 cells by radioligand binding assay
14
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO-K1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Isolation and Pharmacological Characterization of Six Opioidergic <i>Picralima nitida</i> Alkaloids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 14 | 5.23 | 8.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8234 | ENKEPHALIN | — | 2 | 8.92 |
| CHEMBL4846243 | — | — | 2 | 5.10 |
| CHEMBL4871880 | — | — | 2 | 5.00 |
| CHEMBL4856018 | — | — | 2 | 4.82 |
| CHEMBL508955 | AKUAMMICINE | — | 2 | 4.63 |
| CHEMBL4874877 | — | — | 2 | 4.22 |
| CHEMBL4852987 | — | — | 2 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8234 | ENKEPHALIN | Ki | = | 1.2 | nM | 8.92 |
| CHEMBL8234 | ENKEPHALIN | Ki | = | 1.259 | nM | 8.90 |
| CHEMBL4846243 | — | Ki | = | 7943.28 | nM | 5.10 |
| CHEMBL4846243 | — | Ki | = | 8370.0 | nM | 5.08 |
| CHEMBL4871880 | — | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL4871880 | — | Ki | = | 10400.0 | nM | 4.98 |
| CHEMBL4856018 | — | Ki | = | 15000.0 | nM | 4.82 |
| CHEMBL4856018 | — | Ki | = | 15848.93 | nM | 4.80 |
| CHEMBL508955 | AKUAMMICINE | Ki | = | 23200.0 | nM | 4.63 |
| CHEMBL508955 | AKUAMMICINE | Ki | = | 25118.86 | nM | 4.60 |
| CHEMBL4874877 | — | Ki | = | 60300.0 | nM | 4.22 |
| CHEMBL4874877 | — | Ki | = | 63095.73 | nM | 4.20 |
| CHEMBL4852987 | — | Ki | = | 98800.0 | nM | 4.00 |
| CHEMBL4852987 | — | Ki | = | 100000.0 | nM | 4.00 |