Assay Detail
Functional
CHEMBL4817815
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Antiviral activity against Marburgvirus Angola infected in African green monkey Vero cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Marburgvirus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Enantiomeric 4'-truncated 6'-fluoro-3-deazaneplanocin and its 3-bromo derivative: Synthesis and antiviral properties, including Ebola and Marburg.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.64 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4874341 | — | — | 1 | 7.00 |
| CHEMBL4853962 | — | — | 1 | 6.28 |
| CHEMBL221722 | FAVIPIRAVIR | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4874341 | — | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL4853962 | — | EC50 | = | 520.0 | nM | 6.28 |
| CHEMBL221722 | FAVIPIRAVIR | EC50 | = | 155000.0 | nM | - |