Assay Detail
Functional
CHEMBL4819425
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human K562/VCR cells incubated for 72 hrs by CCK8 assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562/VCR |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances of podophyllotoxin/epipodophyllotoxin hybrids in anticancer activity, mode of action, and structure-activity relationship: An update (2010-2020).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.96 | 7.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4862444 | — | — | 1 | 7.09 |
| CHEMBL4850506 | — | — | 1 | 7.09 |
| CHEMBL4854840 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4862444 | — | IC50 | = | 81.0 | nM | 7.09 |
| CHEMBL4850506 | — | IC50 | = | 81.0 | nM | 7.09 |
| CHEMBL4854840 | — | IC50 | = | 202.0 | nM | 6.70 |